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Veterinary Pathology, Vol 15, Issue 1 102-113, Copyright © 1978 by American College of Veterinary Pathologists

ARTICLES

An electron microscopic study of experimentally-induced HEV encephalitis

C. Meyvisch and J. Hoorens

A gnobiotic piglet, was inoculated intracerebrally with hemagglutinating encephalomyelitis virus (strain VW572). Mononuclear cells formed vascular cuffs and were disseminated in the brain parenchyma. A few neurons were surrounded by the same kind of cells. Virus particles morphologically similar to coronavirus particles were found in the cytoplasm of both chromatolytic light neurons and hyperchromic dark neurons. The particles were in vesicles of distended endoplasmic reticulum and in the hypertrophied Golgi apparatus.




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Copyright © 1978 by the American College of Veterinary Pathologists.