Vet Pathol Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chenier, S.
Right arrow Articles by Dore, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chenier, S.
Right arrow Articles by Dore, M.

Veterinary Pathology, Vol 36, Issue 1 74-76, Copyright © 1999 by American College of Veterinary Pathologists

ARTICLES

Oral malignant melanoma with osteoid formation in a dog

S. Chenier and M. Dore

Melanomas are the most frequent malignant neoplasms of the oral cavity of dogs. Osteogenic melanoma is a rare variant of melanoma that has been described in humans but not in animals. We describe a case of malignant melanoma with bone production affecting the gingiva of a 12-year-old Miniature Dachshund dog. The tumor was a round, lightly pigmented mass that measured 1 cm in diameter and was hard to cut. Histologically, the tumor was composed of nests and lobules of anaplastic, round, melanin-containing cells supported by a stroma displaying abundant osteoid matrix. Many of the neoplastic melanocytic cells were in close contact with the osteoid trabeculae. Immunohistochemical tests revealed that the neoplastic cells were immunoreactive for S-100 and vimentin and showed no staining with cytokeratin. The animal had a local recurrence of the tumor 3 months after the initial excision. This is the first case of malignant melanoma with osteoid formation reported in animals.


This article has been cited by other articles:


Home page
 Vet PatholHome page
J. Sanchez, G. A. Ramirez, A. J. Buendia, M. Vilafranca, C. M. Martinez, J. Altimira, and J. A. Navarro
Immunohistochemical Characterization and Evaluation of Prognostic Factors in Canine Oral Melanomas with Osteocartilaginous Differentiation
Vet. Pathol., September 1, 2007; 44(5): 676 - 682.
[Abstract] [Full Text] [PDF]

Home page
 Journal of the American Animal Hospital AssociationHome page
D. G. Hicks and J. L. Fidel
Intranasal malignant melanoma in a dog.
J. Am. Anim. Hosp. Assoc., November 1, 2006; 42(6): 472 - 476.
[Abstract] [Full Text] [PDF]

Home page
 Vet PatholHome page
S. H. Smith, M. H. Goldschmidt, and P. M. McManus
A Comparative Review of Melanocytic Neoplasms
Vet. Pathol., November 1, 2002; 39(6): 651 - 678.
[Abstract] [Full Text] [PDF]

Home page
 Vet PatholHome page
J. A. Ramos-Vara, M. E. Beissenherz, M. A. Miller, G. C. Johnson, L. W. Pace, A. Fard, and S. J. Kottler
Retrospective Study of 338 Canine Oral Melanomas with Clinical, Histologic, and Immunohistochemical Review of 129 Cases
Vet. Pathol., November 1, 2000; 37(6): 597 - 608.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1999 by the American College of Veterinary Pathologists.