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Marginal Siderosis and Degenerative Myelopathy: a Manifestation of Chronic Subarachnoid Hemorrhage in a Horse with a Myxopapillary Ependymoma

Abstract

Marginal siderosis is recognized in humans as an uncommon clinicopathologic entity characterized by degeneration of neural tissue at the surface of the brain and spinal cord, in association with the accumulation of hemosiderin, and resulting from chronic subarachnoid hemorrhage. The sources of hemorrhage are various and include neoplasms, malformations, cysts, and vasculopathy. Marginal siderosis of the spinal cord due to a myxopapillary ependymoma was diagnosed in a 19-year-old Dutch Warm Blood horse with clinical signs of myelopathy. There is only one previous report of marginal siderosis in the veterinary literature, also in a horse with clinical myelopathy.

Key words: Ependymoma; horses; marginal siderosis; myelopathy.

Requests for reprints from Dr. C. R. Huxtable, Department of Biomedical Science, College of Veterinary Medicine, Cornell University, Ithaca NY14853 (USA).

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