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Vet Pathol 41:532-534 (2004)
© 2004 American College of Veterinary Pathologists


BRIEF COMMUNICATIONS AND CASE REPORTS

Multifocal Pleural Cystic Squamous Metaplasia in a Horse with Chronic Obstructive Bronchopneumonia

B. Baum, M. Hewicker-Trautwein and P. Wohlsein

Abstract

A 10-year-old Knabstrupper stallion was euthanatized because of severe dyspnea and exercise intolerance. Postmortem examination revealed diffuse severe alveolar emphysema and chronic fibrosing pleuritis of the caudal lung. Parts of both caudal lung lobes were covered with multiple raised firm gray to yellow plaques. Histologically, these areas consisted of circumscribed pleural fibroses and cysts of metaplastic keratinizing squamous epithelium. Immunohistochemistry revealed intense labeling for cytokeratins 5/6 and 10. In addition, caudal lung lobes were severely affected by a chronic partially obliterative bronchiolitis and peribronchiolitis with multifocal pleural involvement.


Key words: Horses; immunohistochemistry; keratin; lung; metaplasia; pleura.

Request reprints from Dr. B. Baum, Institut für Pathologie der Tierärztlichen Hochschule Hannover, Bünteweg 17, D-30559 Hannover (Germany). E-mail: berit.baum{at}tiho-hannover.de







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Copyright © 2004 by the American College of Veterinary Pathologists.