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Kaposiform Hemangioendothelioma: The First Reported Case in a Nonhuman Animal Species

Abstract

Kaposiform hemangioendothelioma is a rare vascular tumor that almost exclusively occurs in children. It is a low-grade malignant neoplasm that is locally aggressive but without proven metastatic potential. Herein, we describe a case of Kaposiform hemangioendothelioma in a 10-year-old male dog. To the best of our knowledge, this is the first report of this vascular tumor occurring in a nonhuman animal species. The tumor was located on the ventromedial surface of the posterior limb. Microscopic examination of the lesion revealed a multinodular tumor with sheets of spindled endothelial cells forming vascular slits similar to Kaposi's sarcoma and peripheral tumor lobules resembling capillary hemangioma.

Key words: Dalmatian dogs; histopathology; Kaposiform hemangioendothelioma; skin; vascular tumors.

Request reprints from Dr. V. Vincek, Department of Pathology, University of Miami/Jackson Memorial Medical Center, 1611 North West 12 Avenue, Holtz Center, Room 2042, Miami, FL 33136 (USA). E-mail: vvincek{at}med.miami.edu

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