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Vet Pathol 42:663-665 (2005)
© 2005 American College of Veterinary Pathologists
BRIEF COMMUNICATIONS AND CASE REPORTS

Two Cases of Feline Malignant Craniopharyngioma

T. Nagata, H. Nakayama, K. Uchida, K. Uetsuka, A. Yasoshima, S. Yasunaga, K. Masuda, H. Tsujimoto, E. Kuwajima, R. Nishimura, N. Sasaki and K. Doi

Abstract

Tumors at the cranial base in 2 cats (a 91/2-year-old, castrated male Chinchilla and a 7-year-old, castrated male American Shorthair) were diagnosed as malignant craniopharyngioma. The tumor lesion was histopathologically divided into four parts: 1) a small acinus part, in which relatively large cells with a pale cytoplasm composed small acini; 2) a duct part, in which small cuboidal cells composed ducts; 3) a cyst part, in which there were large cysts lined with flat cells; and 4) a pavement part, in which large multiangular-shaped cells proliferated in a pavement pattern. The epithelial cells of some parts were positive for keratin by immunohistochemistry. Histopathologic findings of the present feline cases were identical to those of malignant craniopharyngioma in other animal species.

Key words: Cats; malignant craniopharyngioma.

Request reprints from Dr. Hiroyuki Nakayama, Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, 1-1-1 Yayoi, Bunkyoku, Tokyo 113-8657 (Japan). E-mail: anakaya{at}mail.ecc.u-tokyo.ac.jp.






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