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Vet Pathol 43:186-188 (2006)
© 2006 American College of Veterinary Pathologists


BRIEF COMMUNICATIONS AND CASE REPORTS

Vaginal Rhabdomyosarcoma in a Dog

K. Suzuki, K. Nakatani, H. Shibuya and T. Sato

Abstract

A 10-year-old, female, mongrel showed hemorrhage from vulva. By magnetic resonance image (MRI) and endoscopic examination, a multipapillary mass with a grape-like appearance was found around the urethral opening. Histologically, the mass consisted of variable-sized round-, spindle-to-polygonal–shaped tumor cells including many multinuclear cells. Mitotic figures were also frequently observed. In some areas, that tumor cells were loosely arranged, with intercellular myxoid components. Immunohistochemically, these tumor cells were strongly positive for vimentin and focally positive for desmin but negative for myoglobin. Thus, the case was diagnosed as a relatively poorly differentiated botryoid rhabdomyosarcoma by the macroscopic, histopathologic, and immunohistochemical identification. This is the first report of botryoid rhabdomyosarcoma developing in the vagina of a dog.


Key words: Dogs; histopathology; rhabdomyosarcoma; vagina.

Request reprints from Dr. K. Suzuki, College of Bioresource Sciences, Nihon University, Department of Veterinary Pathology, 1866 Kameino, Fujisawa, Kanagawa 252-8510 (Japan). E-mail: kazuhiko{at}brs.nihon-u.ac.jp




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J.-Y. Yhee, D.-H. Kim, D.-N. Hwang, C.-T. Moon, C.-H. Yu, H.-Y. Kim, A. R. Doster, and J.-H. Sur
Hematogenous metastasis of embryonal rhabdomyosarcoma originating from skeletal muscle in a young dog
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