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Vet Pathol 45:104-108 (2008)
© 2008 American College of Veterinary Pathologists
BRIEF COMMUNICATIONS AND CASE REPORTS

High-Grade Mucoepidermoid Carcinoma of the Mandibular Salivary Gland in a Lion (Panthera leo)

L. Dorso, E. Risi, S. Triau, S. Labrut, F. Nguyen, L. Guigand, M. Wyers and J. Abadie

Unité d'Anatomie Pathologique, UMR ENVN-INRA 703 (LD, SL, FN, LG, MW, JA), and Clinique des Animaux d'Espèces Inhabituelles (ER), Ecole Nationale Vétérinaire de Nantes, Nantes, France, and Service d'Anatomo-Pathologie, CHU Angers, Angers, France (ST)

Abstract

A 13-year-old neutered male lion was presented with a primary neoplasm arising from the left mandibular salivary gland associated with metastases to regional lymph nodes, thoracic viscera (lungs, heart, esophagus, and diaphragm), and kidney. Histologic and immunohistochemical investigations led to a diagnosis of a high-grade mucoepidermoid carcinoma of the mandibular salivary gland. In this case report, we point out the importance of the immunohistochemical characterization for differential diagnosis between various types of carcinomas of the salivary gland.

Key words: Lions; mucoepidermoid carcinoma; p63 antigen; salivary glands.

J Abadie, Unité d'Anatomie Pathologique, Ecole Nationale Vétérinaire de Nantes, BP 40706, 44307 Nantes Cedex 03 (France). E-mail: abadie{at}vet-nantes.fr






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